Hier finden Sie Publikationen von GKM Mitarbeitern und zu Projekten, die die GKM durchgeführt oder unterstützt hat.


Traussnigg S., Schattenberg J.M., Demir M., Wiegand J., Geier A., Teuber G., Hofmann W.P., Kremer A.E., Spreda F, Kluwe J., Petersen J., Boettler T., Rainer F., Halilbasic E., Greinwald R., Pröls M., Manns MP., Fickert P., Trauner M., on behalf of the Austrian/German NAFLD-norUDCA study group

Norursodeoxycholic acid versus placebo in the treatment of non-alcoholic fatty liver disease: a double-blind,
randomised, placebo-controlled, phase 2 dose-finding trial
Lancet Gastroenterol Hepatol 2019
Published Online July 22, 2019; DOI: 10.1016/S2468-1253(19)30184-0

F. Behrens, M. Koehm, EC. Schwaneck, M. Schmalzing, BM. Wittig, H. Gnann, G. Greger, H-P. Tony & H Burkhardt (2019)

Addition or removal of concomitant methotrexate alters adalimumab effectiveness in rheumatoid arthritis but not psoriatic arthritis, Scandinavian Journal of Rheumatology,
first published online July 16.2019, DOI: 10.1080/03009742.2019.1600717

Augsburger M., Sarra G-M., Imesch P.

Treat and extend versus pro re nata regimens of ranibizumab and aflibercept in neovascular age-related macular degeneration: a comparative study
Graefe’s Archive for Clinical and Experimental Ophthalmology
First Online: 29 June 2019

Zanos P., Keyworth H., Georgiou P., Hambsch B., Otte D. M., Kitchen I., Zimmer A., Bailey A.

Chronic nicotine administration restores brain region specific upregulation of oxytocin receptor binding levels in a G72 mouse model of schizophrenia
European Journal of Neuroscience , January 2019


Ancuța C., Petrariu L. A., Opriș Belinski D.
Activitatea fizică la pacienţii cu poliartrită reumatoidă trataţi cu adalimumab în practica clinică: Studiul PACE – rezultate locale România
ePoster Congresul Naţional de Reumatologie a XXV-a editie 12 Octombrie 2018 Poiana Brasov, Romania

Codreanu C , Ancuța C., Bojincă M., Opriș Belinski D.
Impactul tratamentului cu adalimumab: rezultate clinice, utilizarea resurselor de asistenţă medicală (inclusiv concedii medicale) la pacienții cu spondilita anchilozantă în practica clinică: studiul IDEA -rezultate locale România
e-Poster /prezentare Congresul Național De Reumatologie Ediția a XXV-a editie 12 Octombrie 2018 Poiana Brasov, Romania

Miehlke S., Aust D., Mihaly E., ArmerdingP., Böhm G., Bonderup O., Fernández-Bañares F., Kupcinskas J., Munck L., RehbehnK.-U., Nacak T., Greinwald R., and Münch A., on behalf of the BUG-1/LMC Study Group
Efficacy and Safety of Budesonide, vs Mesalazine or Placebo, as Induction Therapy for Lymphocytic Colitis.
Gastroenterology 2018 (available online 7 September 2018)

Dignass A., Schnabel R., Romatowski J., Pavlenko V., Dorofeyev A., Derova J., Jonaitis L., Dilger K., Nacak T. and Greinwald R.; the International SAT-25 Study Group
Efficacy and safety of a novel high-dose mesalazine tablet in mild to moderate active ulcerative colitis: a double-blind, multicentre, randomised trial
United European Gastroenterol J. 2018 Feb; 6(1):138-147

Behrens F., Koehm M., Schwaneck E. C., Schmalzing M., Gnann H., Greger G., Tony H.-P., Burkhardt H.
Minimal disease activity is a stable measure of therapeutic response in psoriatic arthritis patients receiving treatment with adalimumab. Rheumatology July 2018


Berges R., Schremmer D., Limberg R. Avanafil for the treatment of erectile dysfunction in practice. Non-interventional study AVANTI. MMW Fortschr Med. 2017 Jun;159(Suppl 5):16-21. doi: 10.1007/s15006-017-9804-1, 2017

Patchev A., Lux H. SAE Reporting im Zeitalter der Digitalisierung. CRpro, Ausgabe 2, Mai 2017

Röthler A. Vigilanzsystem Experteninhalt, InnovationsLOTSE,, 2017

Khobzey K., Liskova I., Szegedi A., Pavlovsky L., Lunder T., Kingo K., Miljković J., Péč J., Bohinc M., Hojnik M. Effectiveness of adalimumab in the treatment of scalp and nail affection in patients with moderate to severe plaque psoriasis in routine clinical practice. Acta Dermatovenerol Alp Pannonica Adriat. 26(1):11-14, 2017

Laux G., Barthel B., Hajak G., Lemke M., Volz H.-P. Pooled Analysis of Four Non-Interventional Studies: Effectiveness and Tolerability of the Antidepressant Agomelatine in Daily Practice. Adv Ther. 2017 Feb 18. doi: 10.1007/s12325-017-0485-z. [Epub ahead of print], 2017

Röthler A. Post Market Surveillance (PMS) Experteninhalt, InnovationsLOTSE,, 2017

Röthler A. Post Market Clinical Follow-up (PMCF) Experteninhalt, InnovationsLOTSE,, 2017


Michetti P., Weinman J., Mrowietz U., Smolen J., Peyrin-Biroulet L., Louis E., Schremmer D., Tundia N., Nurwakagari P., Selenko-Gebauer N. Impact of Treatment-Related Beliefs on Medication Adherence in Immune-Mediated Inflammatory Diseases: Results of the Global ALIGN Study. Advances in Therapy, first published online: November 16, 2016, doi: 10.1007/s12325-016-0441-3, 2016

Scharbatke E. C., Behrens F., Schmalzing M., Koehm M., Greger G., Gnann H., Burkhardt H., Tony H.-P. Association of Improvement in Pain With Therapeutic Response as Determined by Individual Improvement Criteria in Patients With Rheumatoid Arthritis. Arthritis Care Res (Hoboken); 68(11):1607-1615, 2016

Losch F.-P., Holtkamp M., McMurray R., Lendemans D., Kockelmann E. Antikonvulsive Zusatztherapie mit Eslicarbazepinacetat – Ergebnisse der EPOS-Studie bei Erwachsenen in Deutschland. Nervenarzt (2016), doi:10.1007/s00115-016-0199-5, 2016

Patchev A., Röthler A., Schremmer D., Patchev S. Der „NIS-Lotse“: Antworten auf häufige Fragen bei der Planung einer nicht-interventionellen Studie. Pharmazeutische Medizin 02/16, 2016

Behrens F., Koehm M., Thac D., Gnann H., Greger G., Wittig B.M., Burkhardt H. Anti-citrullinated protein antibodies are linked to erosive disease in an observational study of patients with psoriatic arthritis. Rheumatology, first published online: June 21, 2016, doi: 10.1093/rheumatology/kew229, 2016

Ottiger C., Gygli N., Huber A.R., Fernandez-Tresguerres B., Pardo S., Petruschke T. Performance of a Blood Glucose Monitoring System in a Point-of-Care Setting. Journal of Diabetes Science and Technology. 2016 Mar 16. pii: 1932296816638854, 2016

Holtkamp M., McMurray R., Bagul M., Sousa R., Kockelmann E. Real-world data on eslicarbazepine acetate as add-on to antiepileptic monotherapy. Acta Neurol Scand; Article first published online: 24 FEB 2016, DOI: 10.1111/ane.12574, 2016


Scholtz A.W., Ilgner J., Loader B., Pritschow B.W., Weisshaar G. Cinnarizine and dimenhydrinate in the treatment of vertigo in medical practice. Wien Klin Wochenschr; 2015 Dec 11. [Epub ahead of print], 2015

Volz H.-P., Escafit-Schülke M.-L. Effekte von Agomelatin bei depressiven Patienten im Praxisalltag – Ergebnisse der nicht interventionellen Studie VIVRE. Nervenheilkunde; 34: 809-817, 2015

Eisenhardt A., Schneider T., Scheithe K., Colling C., Heidenreich A., TRIPTOSIX-Studiengruppe. Lebensqualität von Patienten mit Prostatakarzinom unter Androgendeprivation mit GnRH-Analoga – Ergebnisse der nicht-interventionellen Studie TRIPTOSIX. Der Urologe; First online: 01 November 2015, doi:10.1007/s00120-015-3989-7, 2015

Patchev A., Otto A., Engler C., Obermeier M. AMNOG: Was bei der Endpunktwahl für Zulassungsstudien zu berücksichtigen ist. Pharmazeutische Medizin; 17(3): 134-139, 2015

Bedini J.L., Wallace J.F., Petruschke T., Pardo S. A Multicenter Performance Evaluation of a Blood Glucose Monitoring System in 21 Leading Hospitals in Spain. J Diabetes Sci Technol; pii: 1932296815598777 [Epub ahead of print] PubMed PMID: 26253142, 2015

Bedini J.L., Wallace J.F., Pardo S., Petruschke T. Performance Evaluation of Three Blood Glucose Monitoring Systems Using ISO 15197: 2013 Accuracy Criteria, Consensus and Surveillance Error Grid Analyses, and Insulin Dosing Error Modeling in a Hospital Setting. J Diabetes Sci Technol; pii: 1932296815609368 [Epub ahead of print] PubMed PMID: 26445813, 2015

Rothermel J., Scheithe K., Nazari N., Hauffa BP., Reniehr T. Adherence to Growth Hormone Treatment: Impact of Height, Age and Puberty. Poster presentation, European Society for Paediatric Endocrinology (ESPE) Congress 2015; Poster P3-936 Abstract 530; Barcelona, 1-3 October, 2015

Laux G., Barthel B., Hajak G., Lemke M., Volz H.P. Wirk- und Verträglichkeitsprofil des Antidepressivums Agomelatin in der täglichen Praxis. Gepoolte Analyse von vier nicht-interventionellen Studien. Psychopharmakotherapie; 22:136-47, 2015

Engler C., Michelson G. Talkingeyes® – an ISO certified telemedical eye examination network as an effective tool for data collection in clinical research. Poster presentation, European Society of Ophthalmology (SOE) Congress 2015, Vienna, 6-9 June 2015.

Feuchtenberger M., Kleinert S., Scharbatke E.C., Gnann H., Behrens F., Wittig B.M., Greger G., Tony H.P. The impact of prior biologic therapy on adalimumab response in patients with rheumatoid arthritis. Clin Exp Rheumatol; 33(3):321-9, 2015.

Merseburger A.S., Scheithe K., Colling C. How patients prefer to learn that they have cancer: Results of a survey on patients’ preference for communication in prostate cancer using the MPP-d (German version of the Measure of Patients’ Preferences). J Clin Oncol 33 (suppl; abstr e20591), 2015.

Thaci D., Behrens F., Greger G., Burkhardt H., Gnann H., Schopf R., Wittig B.M. Association between Skin and Joint Involvement in Patients with Psoriatic Arthritis Treated with Adalimumab: Analysis of Data from a German Non-Interventional Study. Dermatology. 2015;230(3):213-21.

Ziegler R., Eichholz R., Schulz B. Use of a Combined Blood-Glucose- and beta-Ketone-Measuring Device Improves Glycemic Control in Insulin-Treated Patients with Diabetes: The Gold Plus Study. Journal of Diabetes Science and Technology; 1-5, 2015.


Miehlke S., Madisch A., Kupcinskas L., Petrauskas D., Bohm G., Marks H.J., Neumeyer M., Nathan T., Fernández-Banares F., Greinwald R., Mohrbacher R., Vieth M., Bonerdup O.K., and the BUC-60/COC Study Group. Budesonide Is More Effective Than Mesalazine or Placebo in Short-term Treatment of Collagenous Colitis. Gastroentreology; 146(5):1222-1230, 2014.

Patchev A., Rost M., Engler C., Obermeier M., Hautmann C. The impact of German benefit assessment on endpoint selection in clinical research and drug development in Germany – lessons (to be) learned. Poster presentation, 16. Jahreskongress für klinische Pharmakologie, Cologne, October 9 – 10, 2014.

Rost M. An introduction to value dossiers for early benefit assessment in Germany – Part 1: Processes and players. Regulatory Rapporteur; Volume 11, Issue 11: 25-27, 2014.

Rost M. An introduction to value dossiers for early benefit assessment in Germany – Part 2: Demonstration of additional benefit. Regulatory Rapporteur; Volume 11, Issue 12: 29-32, 2014.

Witt C., Jehn M.L., Omid N., Hanisch M., Liebers U., Ehrlich R., Krohn I., Schremmer D. Multicenter study on COPD out-patient healthcare in Germany (ORCAS). Poster presentation, European Respiratory Society Annual Congress Munich, German, September 6–10, 2014.


Hefter H., Benecke R., Erbguth F., Jost W., Reichel G., Wissel J. An open-label cohort study of the improvement of quality of life and pain in de novo cervical dystonia patients after injections with 500 U botulinum toxin A (Dysport). BMJ Open; 3:e001853, doi:10.1136/bmjopen-2012-001853, 2013.

Laux G., Huttner N. Agomelatin in der Depressionsbehandlung über 12 Monate. Follow-up der VIVALDI-Studie. Psychopharmakotherapie; 20: 119-127, 2013.

Braun A., Gnann H., Saracbasi E., Grifka J., Kiltz U., Letschert K., Braun J. Optimizing the identification of patients with axial spondyloarthritis in primary care–the case for a two-step strategy combining the most relevant clinical items with HLA B27. Rheumatology (Oxford) 4;52(8):1418-24, 2013

Behrens F., Tony H.-P., Alten R., Kleinert S., Scharbatke E. C., Köhm M., Gnann H., Tams J., Greger G., Burkhardt H. Development and Validation of a New Disease Activity Score in 28 Joints–Based Treatment Response Criterion for Rheumatoid Arthritis. Arthritis Care & Research Volume 65, Issue 10, pages 1608-1616, 2013


Beer A.M., Fey S., Zimmer M., Teske W., Schremmer D., Wiebelitz K.R. Wirksamkeit und Sicherheit eines homöopathischen Komplexpräparates bei chronischen Rückenschmerzen. Doppelblinde, randomisierte, placebokontrollierte, klinische Studie. MMW (154. Jg): 48-57, 2012.

Nemes L., Pollmann H., Becker T. Interim data on long-term efficacy, safety and tolerability of a plasma-derived factor VIII concentrate in 109 patients with severe haemophilia A. Haemophilia; 1-7, 2012.

Rieckmann P., Heidenreich F., Sailer M., Zettl U.K., Zessack N., Hartung H.P., Gold R. Treatment de-escalation after mitoxantrone therapy: results of a phase IV, multicentre, open-label, randomized study of subcutaneous interferon beta-1a in patients with relapsing multiple sclerosis. Ther Adv Neurol Disord; 5(1):3-12, 2012.

Rost M. Design und Auswertung einer Medizinproduktstudie – nur die Variation einer Arzneimittelstudie? DZKF 3/4 – 2012.


Bidlingmaier C., Kurnik K., Escuriola-Ettingshausen C., Jager R., Klamroth R., Male C., Marosi A., Nemes L., von Stackelberg A., Kreuz W. Immune tolerance induction with a factor VIII concentrate containing con Willebrand factor (Haemoctin SDH®) in 14 patients with severe haemophilia A. Haemophilia; 1-4, 2011.

Eisenbraun J., Scheer R., Kroz M, Schad F., Huber R. Quality of life in breast cancer patients during chemotherapy and concurrenct therapy with a mistletoe extract. Phytomedicine; 18:151-157, 2011.

Espinola-Klein C., Weisser G., Jagodzinski A., Savvidis S., Warnholtz A., Ostad M-A., Gori T., Munzel T. b-Blockers in Patients With Intermittent Claudication and Arterial Hypertension: Results From the Nebivolol or Metoprolol in Arterial Occlusive Disease Trial. Hypertension; 58:148-154, 2011.

Hahn A., Novotny M., Shotekov P.M., Cirek Z., Bognar-Steinberg I., Baumann W. Comparison of Cinnarazine/Dimenhydrinate Fixed Combination with the Respective Monotherapies for Vertigo of Various Origins. Clin Drug Investig; 31 (6): 371-383, 2011.

Hefter H., Kupsch A., Mungersdorf M., Paus S., Stenner A., Jost W., on behalf of the Dysport Cervical Dystonia Study Group. A botulinum toxin A treatment algorithm for de novo mangement of torticollis and laterocollis. BMJ Open; 1:e000196, doi:10.1136/bmjopen-2011-000196, 2011.

Herzog T., Lemmers H.P., Arlt G., Raakow R., Weimann A., Pascher A., Knoefel W. T., Hesse U., Scheithe K., Groll S., Uhl W. Treatment of postoperative ileus with choline citrate-results of a prospective, randomised, placebo-controlled, double-blind multicentre trial. Int J Colorectal Dis; 26:645-652, 2011.

Kleinert S., Tony H.P., Krause A., Feuchtenberger M., Wassenberg S., Richter C., Rother E., Spieler W., Gnann H., Wittig B.M. Impact of patient and disease characteristics on therapuetic success during adalimumab treatment of patients with rheumatoid arthritis: data from a German noninterventional observational study. Rheumatology international; 32(9):2759-67, 2011.

Laux G. und die VIVALDI-Studiengruppe. Antidepressive Therapie mit Agomelatin in der Facharztpraxis – Ergebnisse der VIVALDI-Studie. Psychopharmakotherapie; 18: 18-26, 2011.

Limberg R., Führer K. Einfluss sozioökonomischer Faktoren auf Insulinverordnung und Dauer der Pen-Schulung. In: „Monitor Versorgungsforschung“ (MVF); 03: 34-37, 2001.


Bayas A., Japp G., Fulda U., Kallmann B.A. Injektionshilfen in der Basistherapie der Multiplen Sklerose. Erhebung bei Neurologen, MS-Betreuern und Patienten. Nervenheilkunde; 1-2: 57-62, 2010.

Koester R., Kaehler J., Ebelt H., Soeffker G., Werden K., Meinertz T. Ivabradine in combination with beta-blocker therapy for the treatment of stable angina pectoris in every day clinical practice. Clin Res Cardiol; 2010.

Laux G., Steinmann C. The antidepressant efficacy of agomelatine in daily practice: Interim-analysis of non-interventional study VIVALDI. Poster presentation, 2010 XXVII CINP CONGRESS, Hong Kong, China, June 6–10, 2010.

Recker K. Fortgeschrittenes Prostatakarzinom. Anwendungsbeobachtung: wirksames und verträgliches Hormon-Implantat. Der Urologe; 49, 2010 (Beilage).

Renieri G., Fuhrer K., Scheithe K., Lorenz K., Pfeiffer N., Thieme H. Efficacy and Tolerability of Preservative-Free Eye Drops Containing a Fixed Combination of Dorzolamide and Timolol in Glaucoma Patients. Journal of Ocular Pharmacology and Therapeutics; 26 (6): 596-603, 2010.

Richter J., Rudwaleit M., Scheithe K., Sieper J., Schneider M. Rheumarückenchek: Entwicklung und Evaluation einer deutschsprachigen Screening Instrumentes für Spondylarthritiden. Z Rheumatol; 69 Suppl 1: 1-92, 2010.

Richter J., Rudwaleit M., Scheithe K., Sieper J., Schneider M. Rheumabackcheck: Development and evaluation of a German language screening instrument for spondyloarthritides. Ann Rheum Dis; 69(Suppl3):650, 2010.

Werner A., Stahn A., Schlabs T., Noack T., Koralewski H.E., Scheithe K., Jahn E., Gunga, H.C. Effects of Nebivolol (Nebilet©) on Cardiovascular and Thermoregulatory Functions under Real and Simulated Microgravity Conditions. Oral presentation, Session 1b: Cardiovascular Research II (05) at Life in Space for Life on Earth, 13-18 June 2010, Trieste, Italy, ESA.


Hefter H., Benecke R., Erbguth F., Jost W., Reichel G. Treatment of heterogeneous subtypes of cervical dystonia with Botulinum Toxin A (500 Units Dysport®) – first results of a multicentre open study. Poster presentation, 13th International Congress of Parkinson’s Disease and Movement Disorders, Paris, France, June 7–11, 2009.

Herzog T., Lemmers H.P., Arlt G., Raakow R., Weimann A., Pascher A., Knoefel W. T., Hesse U., Scheithe K., Groll S., Uhl W. Cholincitrat for the treatment of postoperative ileus after colorectal surgery. Results of a multicentre trial. Abstract, Colorectal Congress St. Gallen, 2nd – 4th December 2009.

Köster R., Kaehler J., Meinertz T. for the REDUCTION Study Group. Treatment of stable angina pectoris by ivabradine in every day practice: The REDUCTION Study. Am Heart J; 158: e51-e57, 2009.


Erb C., Gast U., Schremmer D. German register for glaucoma with dry eye. I. Basic outcome with respect to dry eye. Graefes Arch Clin Ophthalmol; 246: 1593-1601, 2008.

Hefter H., Benecke R., Erbguth F., Jost W., Reichel G. Treatment of heterogeneous forms of cervical
dystonia with Botulinum Toxin A (500 Units Dysport®) – first aspects of a multicentre open study -. Poster presentation, Toxins 2008, 12-15 June, Baveno, Lago Maggiore, Italy.

Ludwig M., Zielinski T., Schremmer D., Stumpe K.O. Reproducibility of 3-dimensional ultrasound readings of volume of carotid atherosclerotic plaque. Cardiovascular Ultrasound; 6:42, 2008.


Angstwurm M.W., Engelmann L., Zimmermann T., Lehmann C., Spes C., Abel P., Strauß R., Meier-Hellmann A., Insel R., Radke J., Schuttler J., Gartner R. Selenium in Intensive Care (SIC) study: Results of a prospective randomized, placebo-controlled, multiple-center study in patients with severe systemic inflammatory response syndrome, sepsis, and septic shock. Crit Care Med; 35: 1-9, 2007.

Deuschl G., Vaitkus A., Fox G.C., Roscher T., Schremmer D., Gordin A. Efficacy and Tolerability of Entacapone Versus Cabergoline in Parkinsonian Patients Suffering from Wearing-Off. Movement Disorders; Vol. 22, No. 11, 1550-1555, 2007.

Engels A., Schröer U., Schremmer D. B-Vitamine steigern die Vitalität. MMW Fortschritte der Medizin Nr.49-50 / 2007 (149. Jg).

Parhofer K.G., Munzel F., Krekler M. Effect of the angiotensin receptor blocker irbesartan on metabolic parameters in clinical practice: the DO-IT prospective observational study. Cardiovascular Diabetology; 6:36, 2007.

Schmidt A.C., Graf C., Broxius K., Scholze J. Blood Pressure-Lowering Effect of Nebivolol in Hypertensive Patients with Type 2 Diabetes Mellitus: The YESTONO Study. Clin Drug Invest; 27: 841-849, 2007.

Stumpe K.O., Agabiti-Rosei E., Zielinski T., Schremmer D., Scholze J., Laeis P., Schwandt P., Ludwig
M. Carotid intima-media thickness and plaque volume changes following 2-year angiotensin II-receptor blockade. The Multicentre Olmesartan atherosclerosis Regression Evaluation (MORE) study. Therapeutic Advances in Cardiovascular Disease; 1, 97, 2007.


Huber R.M., Reck M., Gosse H., von Pawel J., Mezger J., Saal J.G., Kleinschmidt R., Steppert C., Steppling H. Efficacy of a toxicity-adjusted topotecan therapy in recurrent small cell lung cancer. Eur Respir J; 27, 1183-1189, 2006.

Rzany B., Ascher B., Fratila A., Monheit G.D., Talarico S., Sterry W. Efficacy and Safety of 3- and 5-Injection Patterns (30 and 50 U) of Botulinum Toxin A (Dysport) for the Treatment of Wrinkles in the Glabella and the Central Forehead Region. Arch Dermatol; Vol 142: 320 – 326, 2006.

Schermund A., Achenbach S., Budde T., Buziashvili Y., Forster A., Guy F., Henein M., Kerkhoff G., Knollmann F., Kukharchuk V., Lahiri A., Leischik R., Moshage W., Scartl M., Siffert W., Steinhagen-Thiessen E., Sinitsyn V., Vogt A., Wiedeking B., Erbel R. Effect of Intensive Versus Standard Lipid-Lowering Treatment With Atorvastatin on the Progression of Calcified Coronary Atherosclerosis Over 12 Months. A Multicenter, Randomized, Double-Blind Trail. Circulation; 113:427-437, 2006.


Ismail C., Schremmer D., Steindl H. Tonsipret is safe and effective in children suffering from uncomplicated respiratory infections. Results of the first non-interventional study. Congress Phytopharmaka and Phytotherapie 2004.

Muhlhofer A., Mrosek S., Schlegel B., Trommer W., Rozario F., Bohles H., Schremmer D., Zoller WG., Biesalki HK. High-dose intravenous vitamin C is not associated with an increase of pro-oxidative biomarkers. European Journal of Clinical Nutrition; 58: 1151-1158, 2004.

Reinartz S., Kohler S., Schlebusch H., Krista K., Giffels P., Renke K., Huober J., Mobus V., Kreienberg R., DuBois A., Sabbatini P., Wagner U. Vaccination of Patients with Advanced Ovarian Carcinoma with the Anti-Idiotype ACA125: Immunological Response and Survival (Phase Ib/II). Clin Cancer Res; 10: 1580-1587, 2004.


Brockow K., Hautmann C., Fotisch K., Rakoski J., Borelli S., Vieths S., Ring J. Orange-induced skin lesions in patients with atopic eczema: evidence for a non-IgE-mediated mechanism. Acta Derm Venereol; 83(1): 44-48, 2003.

Hautmann C., Pfründer D. Sulbactam in Kombination mit ß-Laktam-Antibiotika. Medizin Forum aktuell Nr. 300; Beilage in der Zeitschrift Medizinische Klinik 9, 2003.


Werner G., März R.E., Schremmer D. Assalix for chronic low back pain and arthralgia: Interim analysis of a post-marketing surveillance study. Focus on Alternative and Complementary Therapies; 7: 115, 2002.


Heckmann M., Ceballos-Baumann A.O., Plewig G. Botulinum Toxin A for Axillary Hyperhidrosis (Excessive Sweating). N Engl J Med; Vol. 344, No. 7, February 15: 488-492, 2001.


Hautmann C., Scheithe K. Fluidextrakt aus Agropyron repens bei Harnwegsinfektionen oder Reizblase. Zeitschrift für Phytotherapie; 21: 252-255, 2000.

Hautmann C., Schremmer D. Wirksamkeit und Verträglichkeit von Medivitan® N. Ergebnisse einer multizentrischen Anwendungsbeobachtung. VitaMinSpur; 15: 125-129, 2000.


Hautmann C., Gratzl S., Simon D., Sigusch B., Nestle F.O., Simon H.-U. Kutane Zytokin-produzierende T-Lymphomzellen assoziiert mit Atopie und Hypereosinophilie. Hautarzt; 10-99; 50: 743-747, 1999.

Müller B. Behandlung von Kindern mit akuten Atemwegserkrankungen, Wirksamkeit und Verträglichkeit von Efeublättertrockenextrakt. Ärztliche Praxis Extra; Ausgabe 2, Februar 1999.

Schremmer D., Bognar-Steinberg I., Baumann W., Pytel J. Efficacy and Tolerability of a Fixed Combination of Cinnarizine and Dimenhydrinate in Treatment of Vertigo. Analysis of Data from Five Randomised, Double-Blind Clinical Studies. Clin Drug Invest; 18 (5): 355-368, 1999.

Schweizer J., Hautmann C. Comparison of Two Dosages of Ginkgo Biloba Extract EGb 761 in Patients with Peripheral Arterial Occlusive Disease Fontaine’s Stage IIb: A randomised, double-blind, multicentric clinical trial. Arzneimittel Forschung Drug Research; 49 (II): 900-904, 1999.


Finelli A., Limberg R., Scheithe K. Mistel-Lektin bei Patienten mit Tumorerkrankungen. Diagnostik und Therapie im Bild; Sonderheft 1, 1998.

Hautmann C., Disch R., Borelli S., Simon D. Bronchospasmus nach systemischer Gabe von Methylprednisolon-21-hydrogensuccinat bei oraler Toleranz von Methylprednisolon. Allergo Journal; Vol 7: 203-206, 1998.

Jörg J. Therapie des Morbus Parkinson mit α-Dihydroergocryptin in der neurologischen Praxis. Akt. Neurologie; 25: 198-201, 1998.

Sarnow E., Pfründer D. Azithromycin bei Patienten mit Atemwegserkrankungen. Wiener klinische Wochenschrift; Springer-Verlag, 1998.

Steinhoff B. J. Antiepileptic Pharmacotherapy with Sustained Release Sodium Valproate, Post Marketing Surveillance of Orfiril® 300 retard. Ces a Slov. Neurol. Neurochir., 61/94, No. 6: 291-295, 1998.


Benos J., Braun R., Finelli A., Schremmer D. MEDIVITAN®N (Vitamin B6, B12, Folsäure) bei Alkoholkranken in der Rehabilitation. Sucht; 43 (6): 430-435, 1997.

Hoppe J.E. Treatment of oropharyngeal candidiasis in immunocompetent infants: a randomized multicenter study of miconazole gel vs. nystatin suspension. Pediatric Infectious Disease Journal; 16: 288-293, 1997.

Limberg R. Die Mistel-Lektin-Therapie in der Praxis, Behandlungserfolg mit Lektinol®. Madaus Sonderheft, August 1997.


Diener H.C., Oldenburg J., Schremmer D. Behandlung akuter Migräneattacken mit Sumatriptan s.c. Z Allg Med 1996; 72: 700-706, 1996.

Hippe S.K. Akute Migräne, Risikolos schnell schmerzfrei. Therapiewoche; 5: 296-297, 1996.

Meyer-Wegener J., Schmidramsl H., Reuter H.D., Schremmer D., Karl J. Neue Wege in der Herz-Kreislauf-Therapie. Gesundes Leben; 1/96: 28-29, 1996.

Schremmer D. Kombination pflanzlicher Wirkstoffe senkt offenbar Blutdruck und Gewicht. Ärztezeitung; 55, 1996.


Hasselkus W. Vorteile der niedrigdosierten Biguanid-Therapie. MWI; Nr. 74, Montag 25. April 1994.

Middeke M., Krone W. Effects of Perindopril on Serum Lipids in Hypertensive Patients with Hyperlipidemia. Journal of Cardiovascular Pharmacology; 23: 629-631, 1994.

Overlack A., Adamczak M.D., Bachmann W., Bonner G., Bretzel R.G., Derichs R., Krone W., Lederle R.M., Reimann H.J., Zschiederich H., Stumpe K.O. ACE-Inhibition with perindopril in essential hypertensive patients with concomitant diseases. The American Journal of Medicine; Volume 97: 126-134, 1994.


Bönner G., Lederle R.M., Scholze J., Stumpe K.O. Therapeutic safety of perindopril in the treatment of mild hypertension. Arzneimittelforschung; 43 (8): 852-855, 1993.

Soyka M., Ablus M., Finelli A., Hofstetter S., Immler B., Kathmann N., Holzbach R., Sand P. Prevalence of alcohol and drug abuse in schizophrenic inpatients. Eur Arch Psychiatry Clin Neurosci; 242: 362-372, 1993.

Stumpe K.O., Overlack A. A New Trial of the Efficacy, Tolerability and Safety of Angiotensin-Converting Enzyme Inhibition in Mild Systemic Hypertension with Concomitant Diseases and Therapies. Am J Cardiol; Volume 71: 32E – 37E, 1993.


Papp R., Lehrl S., Frank S., Burger A., Willemsen A., Woelk H., Burkard G., Hippe S.K. Vitalität und Vitalitätsverlust – Begriffe und Messmöglichkeiten. extracta psychiatrica; Jg 6, Heft 4: 37-47, 1992.

Stumpe K.O. Portrait eines Pharmakons: Celiprolol. Hochdrucktherapie: Blutdrucksenkung und was noch? Der Kassenarzt; 5: 53-56, 1992.

Stumpe K.O., Overlack A. Angiotensin-Converting Enzyme Inhibition in Mild Hypertension with Concomitant Diseases and Therapies: An Efficacy, Safety and Compatibility Study of Novel Design, the Perindopril Therapeutic Safety Study. Am J Medicine; Volume 92 (suppl 4B) 98S, 1992.


Frank S., Lehrl S., Papp R., Woelk H., Benos J., Berthermann O., Böther K., Burkard G., Hippe S.K., Schröder U. Zum Einfluss von B- und C-Vitaminen auf Lebensqualität und Vitalität. extracta psychiatrica; Jg. 5, Heft 10: 40-47, 1991.

Gräßel E., Benos J., Böther K., Burkard G., Hippe S.K., Reimann H.J. Verlust- und Überforderungssyndrome in der modernen Gesellschaft aus ärztlicher und medizinpsychologischer Sicht. medwelt; 42: 356-359, 1991.


Mai B. Dyspepsie – eine Herausforderung an ärztliches Denken und Handeln. Interdisziplinärer Workshop, Budapest. International Society of Internal Medicine; 4, Sonderheft, 1990.


Maiwald L., Ewers H.R., Rapp W., Klapdor R., Brilmayer H. Enzynorm®forte – Funktionelle Bedeutung und klinische Wirksamkeit. Workshop unter dem Vorsitz von Prof. Dr. med. M. Classen im Mai 1986. Periodica Medica; Einhorn-Presse Verlag, 1988.


Hippe S.K. Psychodiagnostik, Ein Arzt-Service-Programm stellt sich vor. Pharma-Marketing-Journal; 4/87: 143-144, 1987.

Schmidt W. Zur Therapie der chronischen Bronchitis, randomisierte Doppelblindstudie mit Asthmakhell®. Therapiewoche; 37: 2803-2809, 1987.


Becker W. Funktionelle Schlafstörungen. Besseres Schlafverhalten und bessere Schlafqualität mit dem Phytopharmakon Phytonoxon®. Therapiewoche; 36: 3830-3836, 1986.

Schulte R.M., Burkard G., Hippe S.K., Kuntz H.D. Die Entwicklung eines Psychodiagnostikums für Gastritis-Patienten. Psycho; 12: 950-959, 1986.


Daunderer W. Schonende Behandlung der Altershypertonie. Multizentrische Praxisstudie mit Ergodesit spezial. Fortschritte der Medizin; 103 Jg., Nr. 25: 680-682, 1985.

Daunderer W., Daunderer M. Altershypertonie und Multimorbidität. Hochdruck, 5: 31-34, 1985.

Weede W. Chronische Bronchitis, verträgliche und nebenwirkungsfreie Therapie mit einem Phytopharmakon. Therapiewoche; 35: 5750-5754, 1985.


Franek A. Phytodolor® – Ein neuer Weg in der Rheumatherapie. Rheuma Schmerz & Entzündung; PMI-Verlag, 4, Sonderdruck, 1984.

Heidland A. Bluthochdruck im höheren Lebensalter, Therapeutische Überlegungen. Hochdruck; 5: 28-32, 1984.

Schnelle K. Bedeutung und Häufigkeit von Altershochdruck mit zerebraler Insuffizienz in der täglichen Praxis. Der Praktische Arzt; 26: 1762-1764, 1984.